Importance Diacetylmorphine hydrochloride (the active ingredient in heroin), delivered under
supervision, is effective for the treatment of severe opioid use disorder. However, owing to …

BackgroundSupervised injectable heroin (SIH) treatment has emerged over the past 15
years as an intensive treatment for entrenched heroin users who have not responded to …

AIM: This study aimed to assess the efficacy of the prescription of intravenous diacetylmorphine
(DAM) versus oral methadone with medical and psychosocial support, with a view of …

Since the initial Swiss heroin-assisted treatment (HAT) study conducted in the mid-1990s,
several other jurisdictions in Europe and North America have implemented HAT trials. All of …

Background Studies in Europe have suggested that injectable diacetylmorphine, the active
ingredient in heroin, can be an effective adjunctive treatment for chronic, relapsing opioid …

Background Despite ongoing efforts aimed to improve treatment engagement for people with
substance-related disorders, evidence shows modest rates of utilization as well as client-…

Aim: To describe social characteristics seen among socially excluded drug users in 10 cities
from 9 European countries, and identify which social exclusion indicators (ie housing, …

Background: Although diacetylmorphine has been proven to be more effective than methadone
maintenance treatment for opioid dependence, its direct costs are higher. We compared …

Fundamento: El estudio del estado de salud en las poblaciones penitenciarias se fundamenta
en las evidencias de una salud más deteriorada que la población general y una mayor …

Background Injectable opioid agonist treatment (iOAT) was designed as a pragmatic and
compassionate approach for people who have not benefitted from medication assisted …