International AIDS Society global scientific strategy: towards an HIV cure 2016
…, G Behrens, M Cavazzana, Z Chen, ÉA Cohen… - Nature medicine, 2016 - nature.com
Antiretroviral therapy is not curative. Given the challenges in providing lifelong therapy to a
global population of more than 35 million people living with HIV, there is intense interest in …
global population of more than 35 million people living with HIV, there is intense interest in …
Distinctive roles of furin and TMPRSS2 in SARS-CoV-2 infectivity
The spike protein (S) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
directs infection of the lungs and other tissues following its binding to the angiotensin-…
directs infection of the lungs and other tissues following its binding to the angiotensin-…
Antagonism of tetherin restriction of HIV-1 release by Vpu involves binding and sequestration of the restriction factor in a perinuclear compartment
…, J Binette, J Mercier, A Chiasson, ÉA Cohen - PLoS …, 2010 - journals.plos.org
The Vpu accessory protein promotes HIV-1 release by counteracting Tetherin/BST-2, an
interferon-regulated restriction factor, which retains virions at the cell-surface. Recent reports …
interferon-regulated restriction factor, which retains virions at the cell-surface. Recent reports …
HIV-1 Vpr-Mediated G2 Arrest Involves the DDB1-CUL4AVPRBP E3 Ubiquitin Ligase
Human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) has been shown to cause
G2 cell cycle arrest in human cells by inducing ATR-mediated inactivation of p34cdc2, but …
G2 cell cycle arrest in human cells by inducing ATR-mediated inactivation of p34cdc2, but …
[HTML][HTML] The membrane‐proximal intracytoplasmic tyrosine residue of HIV‐1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells
Budding of retroviruses from polarized epithelial Madin–Darby canine kidney cells (MDCK)
takes place specifically at the basolateral membrane surface. This sorting event is suspected …
takes place specifically at the basolateral membrane surface. This sorting event is suspected …
Modulation of HIV-1-host interaction: role of the Vpu accessory protein
Viral protein U (Vpu) is a type 1 membrane-associated accessory protein that is unique to
human immunodeficiency virus type 1 (HIV-1) and a subset of related simian …
human immunodeficiency virus type 1 (HIV-1) and a subset of related simian …
HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell–mediated killing
…, TNQ Pham, JP Belzile, ÉA Cohen - Blood, The Journal …, 2010 - ashpublications.org
HIV up-regulates cell-surface expression of specific ligands for the activating NKG2D receptor,
including ULBP-1, -2, and -3, but not MICA or MICB, in infected cells both in vitro and in …
including ULBP-1, -2, and -3, but not MICA or MICB, in infected cells both in vitro and in …
The double-stranded RNA-binding protein Staufen is incorporated in human immunodeficiency virus type 1: evidence for a role in genomic RNA encapsidation
…, M Luo, L Bernier, L DesGroseillers, EA Cohen - Journal of …, 2000 - Am Soc Microbiol
Human Staufen (hStau), a double-stranded RNA (dsRNA)-binding protein that is involved in
mRNA transport, is incorporated in human immunodeficiency virus type 1 (HIV-1) and in …
mRNA transport, is incorporated in human immunodeficiency virus type 1 (HIV-1) and in …
HIV persists in CCR6+ CD4+ T cells from colon and blood during antiretroviral therapy
Objectives: The objective of this article is to investigate the contribution of colon and blood
CD4+ T-cell subsets expressing the chemokine receptor CCR6 to HIV persistence during …
CD4+ T-cell subsets expressing the chemokine receptor CCR6 to HIV persistence during …
Incorporation of Vpr into human immunodeficiency virus type 1 requires a direct interaction with the p6 domain of the p55 gag precursor
…, XJ Yao, M Hrimech, N Rougeau, ÉA Cohen - Journal of Biological …, 1999 - ASBMB
The 96-amino acid Vpr protein is the major virion-associated accessory protein of the
human immunodeficiency virus type 1 (HIV-1). As Vpr is not part of the p55 Gag polyprotein …
human immunodeficiency virus type 1 (HIV-1). As Vpr is not part of the p55 Gag polyprotein …