User profiles for Dino Samartzis
 | Dino SamartzisProfessor, Department of Orthopaedic Surgery, RUSH University Medical Center Verified email at rush.edu Cited by 13614 |
[PDF][PDF] Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …
Magnetically controlled growing rods for severe spinal curvature in young children: a prospective case series
Background Scoliosis in skeletally immature children is often treated by implantation of a
rod to straighten the spine. Rods can be distracted (lengthened) as the spine grows, but …
rod to straighten the spine. Rods can be distracted (lengthened) as the spine grows, but …
A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status
Background: Little is known regarding juvenile disc degeneration in individuals with normal
spinal alignment. Consequently, the purpose of this study was to assess the prevalence, …
spinal alignment. Consequently, the purpose of this study was to assess the prevalence, …
Is autograft the gold standard in achieving radiographic fusion in one-level anterior cervical discectomy and fusion with rigid anterior plate fixation?
D Samartzis, FH Shen, EJ Goldberg, HS An - Spine, 2005 - journals.lww.com
Study Design. A review of 66 consecutive patients at a single institution who underwent one-level
anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation with …
anterior cervical discectomy and fusion (ACDF) with rigid anterior plate fixation with …
Pathobiology of Modic changes
Purpose Low back pain (LBP) is the most disabling condition worldwide. Although LBP
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …
relates to different spinal pathologies, vertebral bone marrow lesions visualized as Modic …
Low back pain in older adults: risk factors, management options and future directions
AYL Wong, J Karppinen, D Samartzis - Scoliosis and spinal disorders, 2017 - Springer
Low back pain (LBP) is one of the major disabling health conditions among older adults aged
60 years or older. While most causes of LBP among older adults are non-specific and self-…
60 years or older. While most causes of LBP among older adults are non-specific and self-…
The association of lumbar intervertebral disc degeneration on magnetic resonance imaging with body mass index in overweight and obese adults: a population …
D Samartzis, J Karppinen, D Chan… - Arthritis & …, 2012 - Wiley Online Library
Objective To investigate the association of being overweight or obese with the presence,
extent, and severity of lumbar disc degeneration on magnetic resonance imaging (MRI) in …
extent, and severity of lumbar disc degeneration on magnetic resonance imaging (MRI) in …
Modic changes of the lumbar spine: prevalence, risk factors, and association with disc degeneration and low back pain in a large-scale population-based cohort
FPS Mok, D Samartzis, J Karppinen, DYT Fong… - The spine journal, 2016 - Elsevier
Background Context Modic changes (MC) are bone marrow lesions on magnetic resonance
imaging (MRI), suggestive of being associated with low back pain (LBP). Data on …
imaging (MRI), suggestive of being associated with low back pain (LBP). Data on …
Comparison of allograft to autograft in multilevelanterior cervical discectomy and fusion with rigid plate fixation
D Samartzis, FH Shen, DK Matthews, ST Yoon… - The Spine Journal, 2003 - Elsevier
BACKGROUND CONTEXT: A relatively high pseudarthrosis rate is associated with multilevel
anterior cervical discectomy and fusion (ACDF). Anterior plate fixation increases fusion rate …
anterior cervical discectomy and fusion (ACDF). Anterior plate fixation increases fusion rate …
Deregulated miR‐155 promotes Fas‐mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase‐3
…, XD Yu, ZH Liu, X Cheng, D Samartzis… - The Journal of …, 2011 - Wiley Online Library
The role of apoptosis in the pathogenesis of intervertebral disc degeneration (IDD) remains
enigmatic. Accumulating evidence has shown that the apoptotic machinery is regulated by …
enigmatic. Accumulating evidence has shown that the apoptotic machinery is regulated by …
