Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

AD Judge, V Sood, JR Shaw, D Fang… - Nature …, 2005 - nature.com
Short interfering RNAs (siRNAs) that mediate specific gene silencing through RNA
interference (RNAi) are widely used to study gene function and are also being developed for …

[HTML][HTML] Lack of IL-6 during coxsackievirus infection heightens the early immune response resulting in increased severity of chronic autoimmune myocarditis

MC Poffenberger, N Straka, N El Warry, D Fang… - PLoS …, 2009 - journals.plos.org
Background Chronic myocarditis is often initiated by viral infection, the most common of
which is coxsackievirus infection. The precise mechanism by which viral infection leads to …

Regulatory T-cells protect from type 1 diabetes after induction by coxsackievirus infection in the context of transforming growth factor-β

MJ Richer, N Straka, D Fang, I Shanina, MS Horwitz - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Coxsackievirus infections have long been associated with the induction of type
1 diabetes. Infection with coxsackievirus B4 (CB4) enhances type 1 diabetes onset in NOD …

Toll-like receptor 4-induced cytokine production circumvents protection conferred by TGF-β in coxsackievirus-mediated autoimmune myocarditis

MJ Richer, D Fang, I Shanina, MS Horwitz - Clinical Immunology, 2006 - Elsevier
Coxsackie B virus (CBV) infections are a leading cause of autoimmune myocarditis
associated with inflammatory heart disease and sudden death in young adults. Previously, we …

Novel nonmajor histocompatibility complex–linked loci from mouse chromosome 17 confer susceptibility to viral-mediated chronic autoimmune myocarditis

…, C Aw, N El Wharry, N Straka, D Fang… - Circulation …, 2010 - Am Heart Assoc
Background— Development of viral-induced chronic myocarditis is thought to involve both
environmental and genetic factors. However, to date, no susceptibility genes have been …

Entamoeba histolytica liver abscess

D Fang, D Shu - CMAJ, 2010 - Can Med Assoc
A39-year-old woman presented to the emergency department with a five-day history of fever,
chills, diarrhea, and pain in the right shoulder and right upper quadrant of her abdomen. …

Length of stay and hospital costs among patients admitted to hospital by family physicians

CK Wen, C Chambers, D Fang, G Mazowita… - Canadian Family …, 2012 - cfp.ca
Objective To compare length of stay and total hospital costs among patients admitted to
hospital under the care of family physicians who were their usual health care providers in the …

[PDF][PDF] Attempts to use PCR site-directed mutagenesis to create a non-functional rop gene in the plasmid pBR322

D Fang - J. Exp. Microbiol. Immunol, 2004 - microbiology.ubc.ca
The co-transformation of two ColE1-type plasmids, pBR322 and pUC19 results in the
exclusion of pBR322 from the cell. Several factors could potentially contribute to this exclusion …

ASSESSMENT AND MANAGEMENTOF ANEMIA IN A POPULATION OF CHILDREN LIVING IN THE INDIAN HIMALAYAS: A STUDENT-LED INITIATIVE

…, M Yan, T Ngai, C Huang, D Fang… - UBC Medical …, 2011 - ojs.library.ubc.ca
Objective: To determine the prevalence and etiology of anemia among school-aged
children in Spiti Valley, India, and implement an appropriate management plan. Methods: …

Global impact of the COVID-19 pandemic on subarachnoid haemorrhage hospitalisations, aneurysm treatment and in-hospital mortality: 1-year follow-up

…, D Dippel, L Rinkel, V Dam-Nolen, HK Dianne… - 2022 - med.muni.cz
Background Prior studies indicated a decrease in the incidences of aneurysmal subarachnoid
haemorrhage (aSAH) during the early stages of the COVID-19 pandemic. We evaluated …