Dr. Judy Anderson ‚s research into the role that nitric oxide plays in muscle regeneration will
have many clinical applications for people who have lost muscle mass or injured a muscle …

INTRODUCTION Satellite cells are muscle precursor cells that lie between the extemal
lamina and sarcolemma of skeletal muscle fibers. ln normal adult muscle, these cells are …

Age-related muscle atrophy or sarcopenia results in progressive loss of muscle function and
satellite cells in aging muscle are increasingly refractory to activation that could mitigate …

Muscle satellite cells are quiescent precursors interposed between myofibers and a sheath
of external lamina. Although their activation and recruitment to cycle enable muscle repair …

Skeletal muscle regenerative potential is reduced with aging. We hypothesized that in vitro
activation of muscle satellite cells would be compromised, and that nitric oxide (NO) …

Nitric oxide is a short-lived intracellular and intercellular messenger. The first realisation that
nitric oxide is important in physiology occurred in 1987 when its identity with the …

Satellite cells are myogenic precursors that proliferate, activate, and differentiate on muscle
injury to sustain the regenerative capacity of adult skeletal muscle; in this process, they self …

Skeletal muscle injury activates satellite cells to proliferate as myoblasts and migrate,
differentiate and fuse with existing fibres at the site of injury. Nitric oxide (NO), a free radical …

Essential processes in the regeneration of an injured muscle include proliferation of satellite
cells and vascularization. Myogenesis and angiogenesis are prerequisites for the …

During muscle repair, nitric oxide (NO) has an important role in the activation and
proliferation of muscle satellite cells (MuSC). Our group has shown that increasing …