HIV infection is associated with the progressive loss of CD4 + T cells through their destruction
or decreased production 1 , 2 . A central, yet unresolved issue of HIV disease is the …

The suite of currently used drugs can be divided into two categories – traditional ‘small
molecule’ drugs with typical molecular weights of <500 Da but with oral bioavailability, and much …

SARS-CoV-2-specific memory T cells will likely prove critical for long-term immune
protection against COVID-19. Here, we systematically mapped the functional and phenotypic …

The mechanisms underlying CD4 + T cell depletion in human immunodeficiency virus (HIV)
infection are not well understood. Comparative studies of lymphoid tissues, where the vast …

The European Position Paper on Rhinosinusitis and Nasal Polyps 2012 is the update of
similar evidence based position papers published in 2005 and 2007. The document contains …

Chronic activation of the immune system is a hallmark of progressive HIV infection and better
predicts disease outcome than plasma viral load, yet its etiology remains obscure. Here we …

Background Concerns regarding potential neurological complications of COVID-19 are being
increasingly reported, primarily in small series. Larger studies have been limited by both …

Cytotoxic T lymphocytes (CTLs) are thought to play a crucial role in the termination of the
acute primary HIV-1 syndrome, but clear evidence for this presumption has been lacking. Here …

We use a massive, matched employer-employee database for the United States to analyze
the contribution of firms to the rise in earnings inequality from 1978 to 2013. We find that one-…

Escape from adaptive T cell immunity through transmutation of viral antigenic structure is a
cardinal feature in the pathogenesis of SIV/HIV infection and a major obstacle to antiretroviral …