Evidence based medicine, whose philosophical origins extend back to mid-19th century
Paris and earlier, remains a hot topic for clinicians, public health practitioners, purchasers, …

Doctors always seek to base their decisions on the best available evidence. Often this
evidence represents extrapolations of pathophysiological principles and logic rather than …

… Address reprint requests to David L. Sackett, MD, Centre for Evidence-Based Medicine, …
Ellis J, Mulligan I, Rowe J, Sackett DL: Inpatient general medicine is evidence based. Lancet 346:…

This book is written by three clinical epidemiologists from McMaster University, Ontario,
Canada. It reflects their desire to apply the principles of population epidemiology to the care of …

Publisher Summary This chapter focuses on the bias in analytic research. Case-control studies
are attractive. They can be executed quickly and at low cost, even when the disorders of …

230 Canadian steelworkers with hyper-tension took part in a randomised trial to see if compliance
with antihypertensive drug regimens could be improved. For care and follow-up these …

38 hypertensive Canadian steelworkers who were neither compliant with medications nor at
goal diastolic blood-pressure six months after starting treatment were allocated either to a …

Objective. To standardize outcome measures in systemic lupus erythematosus (SLE). Three
indices were identified which could adequately describe outcome (disease activity, damage …

Background Previous studies have shown that carotid endarterectomy in patients with
symptomatic severe carotid stenosis (defined as stenosis of 70 to 99 percent of the luminal …

Overall rating: Excellent Strengths: Clear, conversational style; simple explanations.
Weaknesses: None Audience: Practitioners at any stage, including clinical clerks This book is …