A novel coronavirus (SARS-CoV-2) emerged as a global threat in December 2019. As the
epidemic progresses, disease modellers continue to focus on estimating the basic …

Most compartmental epidemic models can be represented using the renewal equation. The
value of the renewal equation is not widely appreciated in the epidemiological modelling …

The COVID-19 pandemic has stimulated wastewater-based surveillance, allowing public
health to track the epidemic by monitoring the concentration of the genetic fingerprints of SARS-…

BACKGROUND: Estimates of the case-fatality rate (CFR) associated with coronavirus disease
2019 (COVID-19) vary widely in different population settings. We sought to estimate and …

The reproduction number R and the growth rate r are critical epidemiological quantities.
They are linked by generation intervals, the time between infection and onward transmission. …

The generation interval is the interval between the time when an individual is infected by an
infector and the time when this infector was infected. Its distribution underpins estimates of …

Infectious disease outbreaks are often characterized by the reproduction number R and
exponential rate of growth r. R provides information about outbreak control and predicted final …

Background Safe and effective vaccines could help to end the ongoing Ebola virus disease
epidemic in parts of west Africa, and mitigate future outbreaks of the virus. We assess the …

Background Patient age is one of the most salient clinical indicators of risk from COVID-19.
Age-specific distributions of known SARS-CoV-2 infections and COVID-19-related deaths are …

Generation intervals, defined as the time between when an individual is infected and when
that individual infects another person, link two key quantities that describe an epidemic: the …