Background Recent trials have demonstrated that thromboprophylaxis using direct oral
anticoagulants is effective but associated with a higher rate of major bleeding in intermediate-to-…

Blood glucose–lowering therapies can positively or negatively affect heart function in type 2
diabetes, or they can have neutral effects. Dipeptidyl peptidase 4 (DPP-4) inhibitors lower …

Introduction: Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-COV-2)
were rapidly developed during the COVID-19 pandemic. There is emerging evidence of …

Purpose For emerging adults with chronic medical diseases, the transition from pediatric to
adult health care is often a time of great upheaval, commonly associated with unhealthy self-…

STUDY DESIGN: This is a phase III multicenter open-label randomized controlled trial in
participants with disabling (moderate-to-severe) post-thrombotic syndrome (PTS) due to …

Before 1998, the only known population of the I. scapularis tick in Canada was in Long Point,
Ontario. Driven by climate change, with bird and small mammal migration, the tick’s …

Background Across Canadian Internal Medicine residency programs, a resident's clinical
exposure to hematologic disorders is highly heterogeneous depending on the residency …

Avant 1998, la seule population connue de la tique I. scapularis au Canada s’ observait à
Long Point, en Ontario. En raison des changements climatiques et de la migration des oiseaux …

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by immune-mediated
destruction of platelets, leading to isolated thrombocytopenia and the potential for …

A 77-year-old man with vascular dementia presented to the emergency department with
dyspnea. His medical history included rheumatic mitral stenosis with mechanical mitral valve …