The prevalence of BRAF, NRAS, and p16CDKN2A mutations during melanoma progression
remains inconclusive. We investigated the prevalence and distribution of mutations in these …

Cigarette smoke (CS) inhalation causes an early inflammatory response in rodent airways
by stimulating capsaicin-sensitive sensory neurons that express transient receptor potential …

Context.— There have been major advances in the understanding of melanoma since the
last revision of the World Health Organization (WHO) classification in 2006. Objective.— To …

Background Despite the success of immunotherapy directed at inhibiting of programmed
death-1 (PD-1)/PD-ligand (L)1 signaling, it is not established whether PD-L1 expression …

Purpose Primary care physicians (PCPs) constitute an appropriate target for new interventions
and educational campaigns designed to increase skin cancer screening and prevention. …

BACKGROUND Cutaneous lymphomas expressing a cytotoxic or natural killer (NK) cell
phenotype represent a group of lymphoproliferative disorders for which there is currently much …

Cancer therapies will increasingly be utilized in combination to treat advanced malignancies
so as to increase their long-term efficacy in a greater proportion of patients. In particular, …

Background Because of the many limitations of studies based on the diagnostic setting of
excised lesions, the impact of dermoscopy (epiluminescence microscopy, dermatoscopy) in …

We have used nonlinear imaging to evaluate collagen organization in connective tissue ex‐vivo
samples. Image analysis methods were tested on healthy dermis, normal scars, and …

A dynamic interplay exists between host and tumor, and the ability of the tumor to evade
immune recognition often determines the clinical course of the disease. Significant enthusiasm …