… have been observed movingthrough the cytoplasm at rates of up to 1.5, um/s (7), and it is
hypothesized that actin polymerization is directly required for the movement, as cytochalasin D …

… In calculating d, we controlled for baseline differences between the intervention and control
condition(s) when pre-intervention measure were available (Becker, 1988). A positive effect …

… Institutes of Health grants AI27655 and AI29619 (DA Portnoy). … micrographs were adapted
from Tilney and Portnoy (1989). … micrographs were adapted from Tilney and Portnoy (1989). …

… We also thank Larry Hale for showing one of us (DA Portnoy) his unpublished data on the
role of cytochalasin D and intracellular spread of ShigeUa. This information helped lead to the …

… Cells were grown for 7 d before use in 100-mm petri dishes (Lab-Tek; American Scientific …
passed 1/5 from a confluent monolayer to the coverslips 2 d before use. Bone marrow-derived …

… DA Portnoy has a consulting relationship with and a financial interest in Aduro BioTech,
which stands to benefit from commercialization of the results of this research. A patent covering …

… Ramucirumab is a fully human IgG-1 monoclonal antibody that binds with high affinity (K D
50 pmol/L) to the VEGFR-2 extracellular domain, which prevents binding of all VEGF ligands …

Actin filament assembly at the cell surface of the pathogenic bacterium Listeria monocytogenes
requires the bacterial ActA surface protein and the host cell Arp2/3 complex. Purified Arp2…

Stimulator of interferon genes (STING) is a cytosolic receptor that senses both exogenous
and endogenous cytosolic cyclic dinucleotides (CDNs), activating TBK1/IRF3 (interferon …

Here we have identified 'triple D' (3d), a recessive N-ethyl-N-nitrosourea-induced mutation
and phenotype in which no signaling occurs via the intracellular Toll-like receptors 3, 7 and 9 (…