Effect of alcoholism on hemostasis.

DH Cowan - Seminars in hematology, 1980 - europepmc.org
Ample data exist indicating that alcoholism profoundly affects the hemostatic mechanism. In
alcoholic patients without cirrhosis, the primary effect is on the blood platelet. Both …

Progress of clinical oncology guidelines development using the Practice Guidelines Development Cycle: the role of practitioner feedback.

…, DI Hodson, MS Carey, DH Cowan - Journal of clinical …, 1998 - ascopubs.org
PURPOSE To present an update on the development of oncology practice guidelines (PGs)
using the Practice Guidelines Development Cycle (Cycle), and to present the results of …

The effect of ethanol on hemostatic properties of human blood platelets

MJ Haut, DH Cowan - The American Journal of Medicine, 1974 - Elsevier
Cowan, Department of Medicine, Cleveland … Cowan DH: Thrombokinetic … Cowan DH,
Haut MJ: Platelet function in acute leukemia. J Lab Clin Med 79: 893, 1972. …

Thrombocytopenia of severe alcoholism

DH COWAN, JD HINES - Annals of Internal Medicine, 1971 - acpjournals.org
Factors related to transitory alcohol-related thrombocytopenia were studied in 43 severely
alcoholic patients. Initial platelet counts were less than 100,000/ µl in 15 patients; 100,000 to …

The platelet defect in leukemia. Platelet ultrastructure, adenine nucleotide metabolism, and the release reaction.

DH Cowan, RC Graham… - The Journal of Clinical …, 1975 - Am Soc Clin Investig
The ultrastructure and adenine nucleotide metabolism of platelets from patients with acute
leukemia were studied to elucidate possible mechanisms for the platelet dysfunction …

Studies on the pathogenesis of alcohol-induced sideroblastic bone-marrow abnormalities

JD Hines, DH Cowan - New England Journal of Medicine, 1970 - Mass Medical Soc
Excessive amounts of alcohol were administered to three alcoholic volunteer subjects while
all were on a nutritionally adequate diet except for folate content. In all three subjects folate …

Relationships between spleen, platelets and factor VIII levels

EP Libre, DH Cowan, SP Watkins Jr, NR Shulman - Blood, 1968 - ashpublications.org
(1) The spleen is essential for the Factor VIII elevations observed after adrenalin infusion
and other acutely stressful stimuli. The spleen appears to be capable of either storing and …

Bioavailability of iron in oral ferrous sulfate preparations in healthy volunteers.

SE Walker, TW Paton, DH Cowan… - CMAJ: Canadian …, 1989 - ncbi.nlm.nih.gov
The bioavailability of iron in five ferrous sulfate preparations was studied in 10 healthy male
volunteers. The preparations were an oral solution, two types of film-coated tablets and two …

Plasma cell myeloma: response of melphalan-resistant patients to high-dose intermittent cyclophosphamide

DE Bergsagel, DH Cowan… - Canadian Medical …, 1972 - ncbi.nlm.nih.gov
High-dose intermittent cyclophosphamide was used in the treatment of 19 patients with
plasma cell myeloma who had demonstrated resistance to melphalan. Good objective …

Platelet function and survival in sickle cell disease

MJ Haut, DH Cowan, JW Harris - The Journal of laboratory and …, 1973 - translationalres.com
Platelet survival, recovery, turnover, and aggregation were measured to evaluate a possible
role of the platelet in the pathophysiology of sickle cell disorders. Autologous platelet …