Objective In 1991, the American College of Chest Physicians (ACCP) and the Society of
Critical Care Medicine (SCCM) convened a “Consensus Conference,” the goals of which were “…

ContextIntensive care unit (ICU) physician staffing varies widely, and its association with patient
outcomes remains unclear.ObjectiveTo evaluate the association between ICU physician …

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Measurements and Main Results We linked all 1995 state hospital discharge records (n=
6,621,559) from seven large states with population and hospital data from the US Census, the …

… : Dr Angus had full access to all corticosteroid domain data and all baseline data in the study;
Dr Lewis had full access to all data required for the primary analyses. Together, Drs Angus …

Objective Despite concern over the appropriateness and quality of care provided in an
intensive care unit (ICU) at the end of life, the number of Americans who receive ICU care at the …

Importance Definitions of sepsis and septic shock were last revised in 2001. Considerable
advances have since been made into the pathobiology (changes in organ function, …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

… the principles of the Grading of Recommendations Assessment, Development and Evaluation
(GRADE) system to guide assessment of quality of evidence from high (A) to very low (D) …

Background Sepsis is life-threatening organ dysfunction due to a dysregulated host response
to infection. It is considered a major cause of health loss, but data for the global burden of …