Non-randomised studies of the effects of interventions are critical to many areas of healthcare
evaluation, but their results may be biased. It is therefore important to understand and …

Background The first publication of this review in Issue 3, 2005 included studies up to November
2003. This update adds studies to December 2006 and focuses on application of a new …

Background The mass media frequently cover health related topics, are the leading source
of information about important health issues, and are targeted by those who aim to influence …

OBJECTIVES: To determine effectiveness and costs of different guideline dissemination and
implementation strategies. DATA SOURCES: MEDLINE (1966 to 1998), HEALTHSTAR (…

Minimization is a largely nonrandom method of treatment allocation for clinical trials. We
conducted a systematic literature search to determine its advantages and disadvantages …

Objectives: In an interrupted time series (ITS) design, data are collected at multiple instances
over time before and after an intervention to detect whether the intervention has an effect …

The methods of evaluating change and improvement strategies are not well described. The
design and conduct of a range of experimental and non-experimental quantitative designs …

Background The opportunity to improve care by delivering decision support to clinicians at
the point of care represents one of the main incentives for implementing sophisticated clinical …

Background Primary angle-closure glaucoma is a leading cause of irreversible blindness
worldwide. In early-stage disease, intraocular pressure is raised without visual loss. Because …

OBJECTIVES: To assess whether open angle glaucoma (OAG) screening meets the UK
National Screening Committee criteria, to compare screening strategies with case finding, to …