A human importin-β family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins

MC Lai, RI Lin, SY Huang, CW Tsai, WY Tarn - Journal of Biological …, 2000 - ASBMB
Serine/arginine-rich proteins (SR proteins) are mainly involved in the splicing of precursor
mRNA. RS domains are also found in proteins that have influence on other aspects of gene …

Serum uric acid and progression of kidney disease: a longitudinal analysis and mini-review

CW Tsai, SY Lin, CC Kuo, CC Huang - PloS one, 2017 - journals.plos.org
Background Increasing evidence supports the association between hyperuricemia and
incident chronic kidney disease (CKD); however, there are conflicting data regarding the role of …

Comparative effectiveness of allopurinol, febuxostat and benzbromarone on renal function in chronic kidney disease patients with hyperuricemia: a 13-year inception …

HW Chou, HT Chiu, CW Tsai, IW Ting… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Direct comparisons of the effectiveness of allopurinol with that of other urate-lowering
agents in chronic kidney disease (CKD) populations, as well as guideline …

The 90-day mortality and the subsequent renal recovery in critically ill surgical patients requiring acute renal replacement therapy

…, CW Tsai, CC Shiao, WY Li, FC Hu, PR Tsai… - The American Journal of …, 2009 - Elsevier
BACKGROUND: Particular attention should be paid to postoperative patients that suffer
from severe acute kidney injury (AKI) requiring renal replacement therapy (RRT). METHODS: …

Longitudinal change in estimated GFR among CKD patients: A 10-year follow-up study of an integrated kidney disease care program in Taiwan

CW Tsai, IW Ting, HC Yeh, CC Kuo - PLoS One, 2017 - journals.plos.org
Background This study examined the progression of chronic kidney disease (CKD) by using
average annual decline in estimated GFR (eGFR) and its risk factors in a 10-year follow-up …

Xanthogranulomatous pyelonephritis: critical analysis of 30 patients

…, CF Wu, CC Huang, YJ Lee, WC Lin, CW Tsai… - … Urology and Nephrology, 2011 - Springer
Introduction and objective Xanthogranulomatous pyelonephritis (XGP) is a chronic
inflammatory condition of the kidneys. Nevertheless, disparities between the pre-operative and …

Uric acid predicts adverse outcomes in chronic kidney disease: a novel insight from trajectory analyses

CW Tsai, HT Chiu, HC Huang, IW Ting… - Nephrology Dialysis …, 2018 - academic.oup.com
Background Very little is known about longitudinal trajectories of serum uric acid (SUA) over
the course of chronic kidney disease (CKD). We aimed to determine whether longitudinal …

Coupling molecular dynamics simulations with experiments for the rational design of indolicidin-analogous antimicrobial peptides

CW Tsai, NY Hsu, CH Wang, CY Lu, Y Chang… - Journal of molecular …, 2009 - Elsevier
Antimicrobial peptides (AMPs) have attracted much interest in recent years because of their
potential use as new-generation antibiotics. Indolicidin (IL) is a 13-residue cationic AMP that …

Cystatin C–and creatinine-based estimated glomerular filtration rate, vascular disease, and mortality in persons with diabetes in the US

CW Tsai, ME Grams, LA Inker, J Coresh… - Diabetes Care, 2014 - Am Diabetes Assoc
OBJECTIVE Serum cystatin C is an alternative to serum creatinine for estimating glomerular
filtration rate (GFR), since cystatin C is less influenced by age and muscle mass. Among …

Serum lactate level and mortality in metformin-associated lactic acidosis requiring renal replacement therapy: a systematic review of case reports and case series

HC Yeh, IW Ting, CW Tsai, JY Wu, CC Kuo - BMC nephrology, 2017 - Springer
Background The current practice concerning timing, mode, and dose of renal replacement
therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure …