Interleukin 17A: toward a new understanding of psoriasis pathogenesis

CW Lynde, Y Poulin, R Vender, M Bourcier… - Journal of the American …, 2014 - Elsevier
Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably
over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin …

The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis …

…, P Fleming, S Siu, J Kraft, C Lynde… - Annals of the …, 2015 - ard.bmj.com
The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 12‐week efficacy, safety and speed of response …

…, KK Singh Ohson, K Barber, C Lynde… - British journal of …, 2020 - academic.oup.com
Background Patients with psoriasis value rapid and complete skin clearance. No head‐to‐head
studies have focused on early responses to interleukin (IL)‐17 vs. IL‐23 inhibitors. …

[HTML][HTML] Two phase 3 trials of adalimumab for hidradenitis suppurativa

…, JJ Crowley, C Lynde… - … England Journal of …, 2016 - Mass Medical Soc
Background Hidradenitis suppurativa is a painful, chronic inflammatory skin disease with
few options for effective treatment. In a phase 2 trial, adalimumab, an antibody against tumor …

Efficacy and safety of ivermectin 1% cream in treatment of papulopustular rosacea: results of two randomized, double-blind, vehicle-controlled pivotal studies.

…, M Appell, M Steinhoff, C Lynde… - Journal of drugs in …, 2014 - europepmc.org
Objective To demonstrate the efficacy and safety of once-daily ivermectin 1% cream in subjects
with moderate to severe PPR. Methods Two identically designed, randomized, double-…

Prevalence and epidemiology of onychomycosis in patients visiting physicians' offices: a multicenter Canadian survey of 15,000 patients

AK Gupta, HC Jain, CW Lynde, P MacDonald… - Journal of the American …, 2000 - Elsevier
A prospective, multicenter study to determine the epidemiology of onychomycosis was
performed in the offices of 3 dermatologists and 1 family physician in Ontario, Canada. In the …

[HTML][HTML] Phase 3 trial of nemolizumab in patients with prurigo nodularis

…, C Paul, D Simon, L Naldi, C Lynde… - … England Journal of …, 2023 - Mass Medical Soc
Background Prurigo nodularis is a chronic, debilitating, and severely pruritic neuroimmunologic
skin disease. Nemolizumab, an interleukin-31 receptor alpha antagonist, down-…

A comprehensive approach to the recognition, diagnosis, and severity-based treatment of focal hyperhidrosis: recommendations of the Canadian Hyperhidrosis …

…, A Dansereau, HCH Hong, C Lynde… - Dermatologic …, 2007 - journals.lww.com
BACKGROUND Hyperhidrosis can have profound effects on a patient's quality of life. Current
treatment guidelines ignore disease severity. OBJECTIVE The objective was to establish …

Prevalence and epidemiology of unsuspected onychomycosis in patients visiting dermatologists' offices in Ontario, Canada‐a multicenter survey of 2001 patients

AK Gupta, HC Jain, CW Lynde… - International journal …, 1997 - Wiley Online Library
Background Questionnaire studies have been used to determine the prevalence of onychomycosis
in the United Kingdom and Europe. One disadvantage of this methodology is that the …

The burden of chronic spontaneous urticaria is substantial: real‐world evidence from ASSURE‐CSU

…, C Grattan, K Hollis, A Knulst, JP Lacour, C Lynde… - Allergy, 2017 - Wiley Online Library
Background Chronic spontaneous urticaria ( CSU ) can be debilitating, difficult to treat, and
frustrating for patients and physicians. Real‐world evidence for the burden of CSU is limited. …