Pressure-induced decreases in arterial diameter are accompanied by membrane depolarization
and Ca 2+ entry via voltage-gated Ca 2+ channels. Recent evidence also suggests the …

Marfan syndrome (MFS) is a genetic disorder that frequently leads to aortic root dissection
and aneurysm. Despite promising preclinical and pilot clinical data, a recent large-scale study …

Background Patients with Marfan (MFS) and Loeys–Dietz (LDS) syndromes have been shown
to have abnormal aortic biophysical properties. The purpose of this study was to compare …

Store-operated Ca 2+ entry (SOCE), which is Ca 2+ entry triggered by the depletion of
intracellular Ca 2+ stores, has been observed in many cell types, but only recently has it been …

The calcium content and distribution of the rat uterus were determined employing flame
photometry and Ca 45 determinations. The total uterine calcium concentration was found to be …

Net and radioactive calcium movements were studied in the rat uterus during stimulation
with acetylcholine and high potassium solutions. High potassium did not affect the efflux of …

There are no therapeutics that directly enhance chronic endothelial nitric oxide (NO) release,
which is typically associated with vascular homeostasis. In contrast, angiotensin II (AngII) …

Rationale Endothelial function is strongly associated with vascular health and homeostasis.
However, therapeutically relevant approaches capable of stimulating the protective …

Superficial sarcoplasmic reticulum (SR) regulates smooth muscle force development
directly by Ca 2+ release and removal to and from the cytoplasm (Somlyo and Somlyo. J …

The inducible isoform of nitric oxide synthase (iNOS) is expressed in human and
experimental cardiac allografts and is localized to infiltrating macrophages, cardiac myocytes, …