© 2014 Canadian Medical Association or its licensors CMAJ, June 10, 2014, 186 (9) 655
lines on evidence-based best practices for managing incidental and secondary findings …

Importance Incidental findings on screening and diagnostic tests are common and may
prompt cascades of testing and treatment that are of uncertain value. No study to date has …

Institutional Review Boards (IRBs) are confronted with new challenges in the face of
expanding technologies while fulfll‐ing their existing regulatory mandate to ensure that …

The possibility of generating incidental findings—in both research and clinical contexts—has
long been regarded as a risk of these enterprises. Should incidental findings (IFs) in …

Determining what constitutes an anticipatable incidental finding (IF) from clinical research
and defining whether, and when, this IF should be returned to the participant have been …

During the course of biomedical research, researchers sometimes obtain information on
participants that is outside the aim of the study but may nonetheless be relevant to the …

Background As thousands of healthy research participants are being included in small and
large imaging studies, it is essential that dilemmas raised by the detection of incidental …

Researchers, institutional review boards (IRBs), participants in human subjects research,
and their families face an important but largely neglected problem—how should incidental …

Researchers in the health sciences regularly discover information of potential health
importance unrelated to their object of study in the course of their research. However, there …

Clinical practice guidelines should support clinicians in delivering preventive health
services. Unfortunately, they often do not provide the information we need to have …