Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

C Iskander, DZ Cherney, KK Clemens, SN Dixon… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: Regulatory agencies warn about the risk of acute kidney injury (AKI) after
the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to …

SGLT2 inhibitors and the risk of acute kidney injury in older adults with type 2 diabetes

M Zhuo, JM Paik, DJ Wexler, JV Bonventre… - American Journal of …, 2022 - Elsevier
Rationale & Objective Sodium-glucose cotransporter 2 (SGLT2) inhibitors have been found
to have many benefits for patients with type 2 diabetes. However, whether SGLT2 inhibitors …

Acute kidney injury events in patients with type 2 diabetes using SGLT2 inhibitors versus other glucose-lowering drugs: a retrospective cohort study

C Rampersad, E Kraut, RH Whitlock… - American Journal of …, 2020 - Elsevier
Rationale & Objective Sodium/glucose cotransporter 2 (SGLT2) inhibitors slow the
progression of chronic kidney disease and prevent heart failure events. However, SGLT2 …

Acute renal outcomes with sodium‐glucose co‐transporter‐2 inhibitors: real‐world data analysis

A Cahn, C Melzer‐Cohen, R Pollack… - Diabetes, Obesity …, 2019 - Wiley Online Library
Aim To assess the possible risk of acute kidney injury (AKI) with the use of sodium‐glucose
co‐transporter‐2 inhibitors (SGLT2‐i) as well as changes in estimated glomerular filtration …

Acute kidney injury in patients on SGLT2 inhibitors: a propensity-matched analysis

GN Nadkarni, R Ferrandino, A Chang… - Diabetes …, 2017 - Am Diabetes Assoc
OBJECTIVE Sodium-glucose cotransporter-2 (SGLT2) inhibitors are new medications that
improve cardiovascular and renal outcomes in patients with type 2 diabetes (T2D). However …

Sodium-glucose cotransport protein 2 inhibitors in patients with type 2 diabetes and acute kidney disease

HC Pan, JY Chen, HY Chen, FY Yeh… - JAMA Network …, 2024 - jamanetwork.com
Importance Sodium-glucose cotransport protein 2 inhibitors (SGLT-2is) have demonstrated
associations with positive kidney-related and cardiovascular outcomes in patients with type …

Acute kidney injury with sodium‐glucose co‐transporter‐2 inhibitors: A meta‐analysis of cardiovascular outcome trials

RE Gilbert, KE Thorpe - Diabetes, Obesity and Metabolism, 2019 - Wiley Online Library
Abstract Three, multicentre, large‐scale, randomized, placebo‐controlled trials of
cardiovascular outcomes with sodium‐glucose co‐transporter‐2 (SGLT2) inhibitors have …

Association of continued use of SGLT2 inhibitors from the ambulatory to inpatient setting with hospital outcomes in patients with diabetes: a nationwide cohort study

LG Singh, S Ntelis, T Siddiqui, SL Seliger… - Diabetes …, 2024 - Am Diabetes Assoc
OBJECTIVE Limited data are available on the continuation of outpatient sodium glucose
cotransporter 2 inhibitors (SGLT2is) during hospitalization. The objective was to evaluate …

Safety of sodium-glucose cotransporter-2 inhibitors in patients with CKD and type 2 diabetes: population-based US cohort study

EL Fu, E D'Andrea, DJ Wexler, E Patorno… - Clinical Journal of the …, 2023 - journals.lww.com
Background Limited information exists regarding the safety of sodium-glucose cotransporter-
2 inhibitors (SGLT2i) in patients with CKD treated in routine care. We evaluated the safety of …

Safety of sodium‐glucose cotransporter 2 inhibitors in elderly patients with type 2 diabetes: A meta‐analysis of randomized controlled trials

M Rigato, GP Fadini, A Avogaro - Diabetes, Obesity and …, 2023 - Wiley Online Library
Aim Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) are particularly effective in
preventing adverse outcomes of heart failure and chronic kidney disease, which are highly …