Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

C Iskander, DZ Cherney, KK Clemens, SN Dixon… - Cmaj, 2020 - Can Med Assoc
BACKGROUND: Regulatory agencies warn about the risk of acute kidney injury (AKI) after
the initiation of sodium-glucose cotransporter-2 (SGLT2) inhibitors. Our objective was to …

Association of sulfonylureas with the risk of dementia: a population‐based cohort study

CY Wu, C Iskander, C Wang, LY Xiong… - Journal of the …, 2023 - Wiley Online Library
Background Sulfonylureas are oral glucose‐lowering medications positioned as a second‐line
therapy for type 2 diabetes. Evidence relating them to cognitive decline has been mixed. …

Association of Sodium–glucose cotransporter 2 inhibitors with time to dementia: a population-based cohort study

CY Wu, C Iskander, C Wang, LY Xiong… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Type 2 diabetes (T2D) increases dementia risk, but clear evidence to
recommend interventions that can mitigate that risk remains lacking. This population-based …

Identifying Ontario geographic regions to assess adults who present to hospital with laboratory-defined conditions: a descriptive study

C Iskander, E McArthur, DM Nash… - … Open Access Journal, 2019 - cmajopen.ca
Background: In 2007, an electronic repository called the Ontario Laboratories Information
System (OLIS) was introduced to allow health care providers timely access to laboratory test …

Acute health care use among children during the first 2.5 years of the COVID-19 pandemic in Ontario, Canada: a population-based repeated cross-sectional study

C Iskander, TA Stukel, C Diong, J Guan, N Saunders… - CMAJ, 2024 - Can Med Assoc
Background: The effects of the decline in health care use at the start of the COVID-19 pandemic
on the health of children are unclear. We sought to estimate changes in rates of severe …

Attitudes and opinions of Canadian nephrologists toward continuous quality improvement options

C Iskander, R McQuillan, G Nesrallah… - … Journal of Kidney …, 2017 - journals.sagepub.com
Background and objectives: A shift to holding individual physicians accountable for patient
outcomes, rather than facilities, is intuitively attractive to policy makers and to the public. We …

The role of a resilient information infrastructure in COVID-19 vaccine uptake in Ontario.

R Duchen, C Iskander, H Chung… - Healthcare Quarterly …, 2021 - europepmc.org
The Role of a Resilient Information Infrastructure in COVID-19 Vaccine Uptake in Ontario. -
Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe PMC Menu About …

Comparison of Acute Health Care Utilization Between Patients Receiving In-Center Hemodialysis and the General Population: A Population-Based Matched Cohort …

…, J Gingras, A Aziz, C Iskander… - … Journal of Kidney …, 2024 - journals.sagepub.com
Background: Patients receiving maintenance hemodialysis have multiple comorbidities and
are at high risk of presenting to the hospital. However, the incidence and cost of acute health …

Derivation and external validation of a risk index for predicting acute kidney injury requiring kidney replacement therapy after noncardiac surgery

…, KB Zarnke, E McArthur, C Iskander… - JAMA Network …, 2021 - jamanetwork.com
Importance Severe acute kidney injury (AKI) is a serious postoperative complication. A tool
for predicting the risk of AKI requiring kidney replacement therapy (KRT) after major …

Development and evaluation of a core genome MLST schema for Haemophilus influenzae

M Iskander - 2017 - mspace.lib.umanitoba.ca
Haemophilus influenzae is a human pathogen that can cause disease in young children and
the elderly. While there are several typing methods used for H. influenzae, serotyping and …