User profiles for Brenda R. Hemmelgarn

Brenda Hemmelgarn

University of Calgary
Verified email at albertahealthservices.ca
Cited by 140222

Chronic kidney disease and cardiovascular risk: epidemiology, mechanisms, and prevention

RT Gansevoort, R Correa-Rotter, BR Hemmelgarn… - The Lancet, 2013 - thelancet.com
Since the first description of the association between chronic kidney disease and heart
disease, many epidemiological studies have confirmed and extended this finding. As chronic …

Relation between kidney function, proteinuria, and adverse outcomes

BR Hemmelgarn, BJ Manns, A Lloyd, MT James… - Jama, 2010 - jamanetwork.com
Context The current staging system for chronic kidney disease is based primarily on estimated
glomerular filtration rate (eGFR) with lower eGFR associated with higher risk of adverse …

Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney …

…, KE Griffith, BR Hemmelgarn… - Kidney international …, 2013 - pure.johnshopkins.edu
The Kidney Disease: Improving Global Outcomes (KDIGO) 2012 Clinical Practice Guideline
for the Evaluation and Management of Chronic Kidney Disease (CKD) serves to update the …

Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate

…, CP Wen, J Coresh, RT Gansevoort, BR Hemmelgarn… - Jama, 2012 - jamanetwork.com
Context The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation more
accurately estimates glomerular filtration rate (GFR) than the Modification of Diet in Renal …

Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial

…, MG Friedrich, A Kumar, H Mahallati, BR Hemmelgarn… - Jama, 2007 - jamanetwork.com
ContextMorbidity and mortality rates in hemodialysis patients remain excessive. Alterations
in the delivery of dialysis may lead to improved patient outcomes.ObjectiveTo compare the …

Associations between hemodialysis access type and clinical outcomes: a systematic review

…, NI Pannu, C Thomas, BR Hemmelgarn… - Journal of the …, 2013 - journals.lww.com
Clinical practice guidelines recommend an arteriovenous fistula as the preferred vascular
access for hemodialysis, but quantitative associations between vascular access type and …

Risk of coronary events in people with chronic kidney disease compared with those with diabetes: a population-level cohort study

…, S Klarenbach, N Pannu, MT James, BR Hemmelgarn - The Lancet, 2012 - thelancet.com
Background Diabetes is regarded as a coronary heart disease risk equivalent—ie, people
with the disorder have a risk of coronary events similar to those with previous myocardial …

Early recognition and prevention of chronic kidney disease

MT James, BR Hemmelgarn, M Tonelli - The Lancet, 2010 - thelancet.com
Chronic kidney disease is a common disorder and its prevalence is increasing worldwide.
Early diagnosis on the basis of presence of proteinuria or reduced estimated glomerular …

The NLRP3 inflammasome promotes renal inflammation and contributes to CKD

…, J Tschopp, K Trpkov, BR Hemmelgarn… - Journal of the …, 2010 - journals.lww.com
Inflammation significantly contributes to the progression of chronic kidney disease (CKD).
Inflammasome-dependent cytokines, such as IL-1β and IL-18, play a role in CKD, but their …

[HTML][HTML] Nomenclature for kidney function and disease: report of a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference

…, RT Gansevoort, JS Gill, EL Greene, BR Hemmelgarn… - Kidney international, 2020 - Elsevier
The worldwide burden of kidney disease is rising, but public awareness remains limited,
underscoring the need for more effective communication by stakeholders in the kidney health …