Objective To compare the risk of mortality among people with opioid use disorder on and off
opioid agonist treatment (OAT) in a setting with a high prevalence of illicitly manufactured …

Importance Mortality among people with opioid dependence is higher than that of the general
population. Opioid agonist treatment (OAT) is an effective treatment for opioid dependence…

Background There has been renewed call for the global expansion of highly active antiretroviral
therapy (HAART) under the framework of HIV treatment as prevention (TasP). However, …

Aspects of methadone maintenance treatment (MMT) delivery, particularly daily dosing practices,
are associated with longer retention in treatment. Our objective was to identify trends in …

Background The cascade of HIV care has become a focal point for implementation efforts to
maximise the individual and public health benefits of antiretroviral therapy. We aimed to …

Background and Aims The ‘cascade of care’ framework, measuring attrition at various stages
of care engagement, has been proposed to guide the public health response to the opioid …

Despite decades of experience treating heroin or prescription opioid dependence with
methadone or buprenorphine—two forms of opioid substitution therapy—gaps remain between …

Background: Although diacetylmorphine has been proven to be more effective than methadone
maintenance treatment for opioid dependence, its direct costs are higher. We compared …

STUDY OBJECTIVE: Our objectives are to describe the outcomes of patients presenting to
the emergency department (ED) because of an adverse drug event and to compare them with …

Background. Heterogeneity in HIV microepidemics across US cities necessitates locally
oriented, combination implementation strategies to prioritize resources. We calibrated and …