Evidence suggests that damage to human sperm DNA might adversely affect reproductive
outcomes and that the spermatozoa of infertile men possess substantially more sperm DNA …

While the semen analysis has traditionally been relied upon to differentiate fertile and
infertile men, its utility has been questioned in the current era of assisted reproductive …

The advent of assisted reproductive technologies, particularly intracytoplasmic sperm
injection (ICSI), has revolutionized the treatment of male‐factor infertility. However, there are …

The quality of sperm DNA is very important in maintaining the reproductive potential of men.
Sperm DNA is resistant to many types of insults that occur during its journey from the testis to …

There now exists clinical evidence to show that sperm DNA damage is detrimental to
reproductive outcomes. Tests for DNA damage may provide better prognostic information …

Although it has been thirty years since publication of one of the most influential papers on
the value of assessing sperm DNA damage, andrologists have yet to reach a general …

Many studies have shown how a 'paternal effect'can cause repeated assisted reproduction
failures. In particular, with increasing experience of intracytoplasmic sperm injection (ICSI), it …

Sperm DNA contributes half the offspring's genomic material and abnormal DNA can lead to
derangements in the reproductive process. Normal sperm genetic material is required for …

Sperm deoxyribonucleic acid (DNA) damage has recently emerged as one of the most
controversial topics in male reproductive medicine. While level I evidence indicates that …

Multiple techniques have been developed to measure the amount of sperm DNA damage in
an effort to identify more objective parameters for evaluation of infertile men. We now have …