Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: systematic review and meta-analysis

A Zini, JM Boman, E Belzile, A Ciampi - Human reproduction, 2008 - academic.oup.com
BACKGROUND Sperm DNA damage is common amongst infertile men and may adversely
impact natural reproduction, IUI-assisted reproduction and to a lesser degree IVF pregnancy. …

[HTML][HTML] Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men

A Zini, R Bielecki, D Phang, MT Zenzes - Fertility and sterility, 2001 - Elsevier
Objective: To evaluate two different assays of human sperm DNA integrity, DNA denaturation
(DD) and DNA fragmentation (DF), and to correlate these with standard semen parameters. …

Are sperm chromatin and DNA defects relevant in the clinic?

A Zini - Systems biology in reproductive medicine, 2011 - Taylor & Francis
There has been an increase in the use of sperm DNA and chromatin integrity tests in the
evaluation of the infertile man with the hypothesis that these tests may better diagnose infertility …

Potential adverse effect of sperm DNA damage on embryo quality after ICSI

A Zini, J Meriano, K Kader, K Jarvi… - Human …, 2005 - academic.oup.com
BACKGROUND: Sperm DNA damage is prevalent amongst infertile men and has been
shown to strongly impact adversely natural reproduction, intrauterine insemination-assisted …

[HTML][HTML] Are varicoceles associated with increased deoxyribonucleic acid fragmentation?

A Zini, G Dohle - Fertility and sterility, 2011 - Elsevier
OBJECTIVE: To perform a literature search on the association between varicocele and sperm
DNA fragmentation. DESIGN: Systematic review. PATIENT(S): Men with a varicocele and …

[PDF][PDF] Reactive oxygen species and sperm physiology

E De Lamirande, H Jiang, A Zini, H Kodama… - Reviews of …, 1997 - academia.edu
Although high concentrations of reactive oxygen species (ROS) cause sperm pathology (ATP
depletion leading to insufficient axonemal phosphorylation, lipid peroxidation and loss of …

Varicocele and male factor infertility treatment: a new meta-analysis and review of the role of varicocele repair

…, G Dohle, K Jarvi, A Salonia, W Weidner, A Zini - European urology, 2011 - Elsevier
CONTEXT: Varicocele is a common condition, found in many men who present for infertility
evaluation. OBJECTIVE: To assess the effect of varicocelectomy on male infertility. …

Diagnosis and treatment of infertility in men: AUA/ASRM guideline part I

…, JR Treadwell, JT Oristaglio, A Zini - The Journal of …, 2021 - auajournals.org
Purpose: The summary presented herein represents Part I of the two-part series dedicated
to the Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline. Part I outlines the …

Are tests of sperm DNA damage clinically useful? Pros and cons

A Zini, M Sigman - Journal of andrology, 2009 - Wiley Online Library
The advent of assisted reproductive technologies, particularly intracytoplasmic sperm injection
(ICSI), has revolutionized the treatment of male‐factor infertility. However, there are many …

A systematic review and meta-analysis to determine the effect of sperm DNA damage on in vitro fertilization and intracytoplasmic sperm injection outcome

L Simon, A Zini, A Dyachenko, A Ciampi… - Asian journal of …, 2017 - journals.lww.com
Sperm DNA damage is prevalent among infertile men and is known to influence natural
reproduction. However, the impact of sperm DNA damage on assisted reproduction outcomes …