Obesity prevention efforts in Aboriginal (First Nations, Métis, or Inuit) communities in Canada
should focus predominantly on children given their demographic significance and the …

Nonalcoholic fatty liver disease (NAFLD) is emerging as a component of the metabolic syndrome,
although it is not known whether markers of NAFLD, including elevated concentrations …

A limited number of studies have reported associations of markers of liver injury, including
elevated concentrations of aspartate aminotransferase (AST) and alanine aminotransferase (…

OBJECTIVE—The prospective association between insulin levels and risk of cardiovascular
disease (CVD) is controversial. The objective of the present study was to investigate the …

Background: The prevalence of pediatric obesity in North America is increasing. Native
American children are at especially high risk. Objectives: The objective was to evaluate the …

Factor analysis, a multivariate correlation technique, has been used to provide insight into
the underlying structure of metabolic syndrome, which is characterized by physiological …

OBJECTIVE—To prospectively investigate predictors of the incident metabolic syndrome in
nondiabetic adults. RESEARCH DESIGN AND METHODS—This analysis included 714 white…

Background— In addition to predicting cardiovascular disease (CVD) morbidity and mortality,
the metabolic syndrome is strongly associated with the development of type 2 diabetes …

Acute-phase biomarkers such as C-reactive protein (CRP) and IL-6 have emerged as
predictors of incident type 2 diabetes mellitus, implicating chronic subclinical inflammation as a …

Recent research suggests that tumor necrosis factor-α (TNFα) may play an important role in
obesity-associated insulin resistance and diabetes. We studied the relationship between …