Objectives : We examined the ESCAPE (Evaluation Study of Congestive Heart Failure and
Pulmonary Artery Catheterization Effectiveness) database to understand the impact and …

Measurement of the increase in digital pulse volume amplitude (PVA) during reactive hyperemia
relative to baseline (PVA-RH) is being applied widely as a convenient test of nitric oxide …

Objectives : This study was designed to determine the relevance of a proposed classification
for advanced heart failure (HF). Profiles based on clinical assessment of congestion and …

… Nohria has received research support from Amgen; and has been a consultant for Takeda
Oncology. Dr. Heinzerling has received consultancy, advisory board, and speaker fees from …

ContextAdvanced heart failure, defined as persistence of limiting symptoms despite therapy
with agents of proven efficacy, accounts for the majority of morbidity and mortality in heart …

Investigations from basic biology suggest that activation of the Rho/Rho kinase pathway
reduces the bioavailability of nitric oxide (NO) and thereby promotes atherosclerosis and its …

The discipline of Cardio-Oncology has seen tremendous growth over the past decade. It is
devoted to the cardiovascular (CV) care of the cancer patient, especially to the mitigation and …

Importance COVID-19 is a life-threatening illness for many patients. Prior studies have
established hematologic cancers as a risk factor associated with particularly poor outcomes from …

Advances in cancer therapy have resulted in significant improvement in long-term survival
for many types of cancer but have also resulted in untoward side effects associated with …

BACKGROUND: In addition to inhibiting cholesterol synthesis, statins (HMG-CoA reductase
inhibitors) decrease the formation of isoprenoid intermediates required for the activation of …