Interferon-α (IFN-α) is essential for antiviral immunity, but in the absence of matrix
metalloproteinase-12 (MMP-12) or IκBα (encoded by NFKBIA) we show that IFN-α is retained in the …

BACKGROUND: Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
is associated with high intensive care unit (ICU) mortality. We aimed to describe the clinical …

Today the pharmacological possibilities of treating cancer are expanding and as a result, life
expectancy is increasing against the background of chemotherapy and supportive treatment…

Background Adverse drug events, the unintended and harmful effects of medications, are
important outcome measures in health services research. Yet no universally accepted set of …

Recovery of the contractile function of the heart and the regeneration of the myocardium after
ischemic injury are contemporary issues in regenerative medicine and cell biology. This …

Pulmonary embolism (PE) is the third most prevalent cardiovascular disease. It is associated
with high in-hospital mortality and the development of acute and chronic complications. …

BACKGROUND Trauma-induced coagulopathy contributes to significant morbidity and mortality
in patients who experience trauma-related bleeding. This study aimed to synthesize the …

Aims Trigger tools are retrospective surveillance methods that can be used to identify adverse
drug events (ADEs), unintended and harmful effects of medications, in medical records. …

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and life-threatening
complication of pulmonary embolism. As existing animal models of CTEPH do not fully …

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute
pulmonary embolism with poor clinical outcomes. Therapeutic approaches to prevention of …