The dramatic increase over the past 10 years in the amount of available clinical research on
the use of antidepressants to treat major depression in children and adolescents has …

Background: Depression in children and adolescents is a cause of substantial morbidity and
mortality in this population. It is a common disorder that affects 2% of children and up to 6 …

Major depressive disorder is a common, chronic, recurring, and disabling illness in children
and adolescents. Epidemiologic data suggest that the mean age at onset for depression is …

Significant controversy surrounds the efficacy of the newer antidepressants for children and
adolescents with depression. The controversy largely hinges on meta-analyses of studies …

Major depression is a common disorder during childhood and adolescence. Over the past
decade, many new antidepressants have been marketed in the US. In adults, these newer …

There have been significant developments in the understanding of depression in children
and adolescents in the past few years, including an increased recognition that significant …

Objective: To examine the data on the effect of antidepressant medication in depressed
children and adolescents and the causes of the results obtained. Method: A systematic …

OBJECTIVE: The review examined the historical progression and current status of
pharmacotherapy of child and adolescent major affective disorder. METHODS: A MEDLINE …

Despite the sophistication of the currently available studies on antidepressant treatment of
adolescent depression, various methodological problems limit the conclusions that can be …

Antidepressant agents are widely prescribed for adolescents, although specific data
regarding their efficacy in this age range are limited. The aims of the present article are to …