Syphilis is a chronic disease with a waxing and waning course, the manifestations of which
have been described for centuries. It occurs worldwide, and the incidence varies significantly …

Complexities in the diagnosis of syphilis continue to challenge clinicians. While direct tests (eg,
microscopy or PCR) are helpful in early syphilis, the mainstay of diagnosis remains …

Objectives: Sexual partnerships can be viewed as networks in order to study disease
transmission. We examined the transmission of Neisseria gonorrhoeae in a localised outbreak in …

Background. Chlamydia trachomatis is the most common notifiable disease in Canada, and
extragenital sites are believed to serve as hidden reservoirs for ongoing transmission of …

BACKGROUND: Benzathine penicillin G is the treatment of choice for infectious syphilis, but
tetracycline and doxycycline are believed to be effective second-line treatments. The …

Although detection of Treponema pallidum DNA in whole-blood specimens of syphilis patients
has been reported, it is uncertain at what stage of the disease such specimens are most …

Anal cancer is a rare malignancy of the distal gastrointestinal tract, often associated with
human papillomavirus, the most common sexually transmitted infection worldwide. Currently …

The diagnosis of neurologic and eye/ear involvement with syphilis may be delayed because
of a lack of specificity of findings, low suspicion for syphilis, fluctuation in symptoms, and/or …

Background: Resurgence of syphilis in Canada and worldwide requires laboratories to
update their methods for molecular epidemiology investigation and surveillance. This study …

Objectives Single-visit testing and treatment for syphilis can reduce follow-up visits. The
objectives of this study were to evaluate the performance and treatment outcomes of two dual …