Prediabetes: a high-risk state for diabetes development

AG Tabák, C Herder, W Rathmann, EJ Brunner… - The Lancet, 2012 - thelancet.com
Prediabetes (intermediate hyperglycaemia) is a high-risk state for diabetes that is defined
by glycaemic variables that are higher than normal, but lower than diabetes thresholds. 5–10% …

[HTML][HTML] Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study

AG Tabák, M Jokela, TN Akbaraly, EJ Brunner… - The Lancet, 2009 - thelancet.com
Background Little is known about the timing of changes in glucose metabolism before
occurrence of type 2 diabetes. We aimed to characterise trajectories of fasting and postload …

[HTML][HTML] Prediabetes: a high-risk state for developing diabetes

AG Tabák, C Herder, W Rathmann, EJ Brunner… - Lancet, 2012 - ncbi.nlm.nih.gov
Prediabetes (or “intermediate hyperglycaemia”), based on glycaemic parameters above
normal but below diabetes thresholds is a high risk state for diabetes with an annualized …

Depression and type 2 diabetes: a causal association?

AG Tabák, TN Akbaraly, GD Batty… - The lancet Diabetes & …, 2014 - thelancet.com
There is a controversy regarding whether depression and type 2 diabetes are causally linked.
To assess this issue, we review key findings for the association between depression and …

Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort study

M Hamer, S Sabia, GD Batty, MJ Shipley, AG Tabák… - Circulation, 2012 - Am Heart Assoc
Background— Inflammatory processes are putative mechanisms underlying the
cardioprotective effects of physical activity. An inverse association between physical activity and …

Moving to an A1C-based diagnosis of diabetes has a different impact on prevalence in different ethnic groups

…, V Mohan, JE Shaw, AG Tabák… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To compare screen-detected diabetes prevalence and the degree of diagnostic
agreement by ethnicity with the current oral glucose tolerance test (OGTT)-based and newly …

[HTML][HTML] Midlife type 2 diabetes and poor glycaemic control as risk factors for cognitive decline in early old age: a post-hoc analysis of the Whitehall II cohort study

RH Tuligenga, A Dugravot, AG Tabák… - The lancet Diabetes & …, 2014 - thelancet.com
Background Type 2 diabetes increases the risk for dementia, but whether it affects cognition
before old age is unclear. We investigated whether duration of diabetes in late midlife and …

Accelerated increase in serum interleukin-1 receptor antagonist starts 6 years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study

…, MJ Shipley, DR Witte, EJ Brunner, AG Tabák - Diabetes, 2010 - Am Diabetes Assoc
OBJECTIVE Although interleukin-1 receptor antagonist (IL-1Ra) treatment is associated with
improved β-cell function and glycemic control in patients with type 2 diabetes, its role in the …

Risk of macrovascular and microvascular disease in diabetes diagnosed using oral glucose tolerance test with and without confirmation by hemoglobin A1c: the …

AG Tabák, EJ Brunner, JV Lindbohm… - Circulation, 2022 - Am Heart Assoc
Background: It is unclear whether replacing oral glucose tolerance test (OGTT) with hemoglobin
A1c (HbA1c) measurement for diagnosing diabetes is justified. We aimed to assess the …

[HTML][HTML] Insulin therapy in adults with type 1 diabetes mellitus: a narrative review

…, N Lalic, T Tankova, L Czupryniak, AG Tabák… - Diabetes Therapy, 2020 - Springer
Here, we review insulin management options and strategies in nonpregnant adult patients
with type 1 diabetes mellitus (T1DM). Most patients with T1DM should follow a regimen of …