An artificial endocrine pancreas

AM Albisser, BS Leibel, TG Ewart, Z Davidovac… - Diabetes, 1974 - Am Diabetes Assoc
In order to regulate the blood sugar in the intact depancreatized dog as precisely as that
accomplished by its normal pancreas, specific equipment has been devised to deliver insulin or …

Clinical control of diabetes by the artificial pancreas

AM Albisser, BS Leibel, TG Ewart, Z Davidovac… - Diabetes, 1974 - Am Diabetes Assoc
An artificial pancreas capable of maintaining blood sugar homeostasis within the physiological
range is described in this paper. The blood sugar is continuously monitored and then …

Insulin aggregation in artificial delivery systems

…, H Woulfe-Flanagan, JR Clement, AM Albisser - Diabetologia, 1980 - Springer
Conclusions Abrupt changes in flow path, motion, elevated temperatures, metal ion
contamination, impure insulin formulations, CO 2 diffusion, pH drop, dissimilar metal pump …

Glucoregulatory and metabolic response to exercise in obese noninsulin-dependent diabetes

…, EB Marliss, AK Hanna, AM Albisser… - American Journal …, 1981 - journals.physiology.org
The metabolic response to exercise in obese postabsorptive noninsulin-dependent diabetics
was compared to that of obese nondiabetics. Exercise consisted of 45 min on a cycle …

Intelligent instrumentation in diabetic management.

AM Albisser - Critical reviews in biomedical engineering, 1989 - europepmc.org
This presentation describes the problem of insulin-dependent diabetes mellitus and the
various approaches to creating intelligent instrumentation for management of this type of …

Physical stability of insulin formulations

WD Lougheed, AM Albisser, HM Martindale… - Diabetes, 1983 - Am Diabetes Assoc
Insulin aggregation remains a fundamental obstacle to the long-term application of many
insulin infusion systems. We here report the effects of physiologic and nonphysiologic …

Glucoregulation during moderate exercise in insulin treated diabetics

…, FT Murray, M Vranic, AM Albisser… - The Journal of …, 1977 - academic.oup.com
To characterize glucoregulation during exercise in insulin treated non-obese diabetics, the
response to controlled exercise after an overnight fast was compared to that of normal …

9 the artificial pancreas

AM Albisser, BS Leibel - Clinics in endocrinology and metabolism, 1977 - Elsevier
Diabetes mellitus is a bipartite disease characterized by an immediate need to regulate the
metabolism of carbohydrate, protein and fat and accompanied by an ultimate peril of …

An electronic case manager for diabetes control

LF Meneghini, AM Albisser, RB Goldberg… - Diabetes …, 1998 - Am Diabetes Assoc
OBJECTIVE To evaluate the usage and safety of an electronic case manager (ECM) system
designed to facilitate the task of glycemic control. Sustained improvement in blood glucose …

Computer-assisted insulin dosage adjustment

A Schiffrin, M Mihic, BS Leibel, AM Albisser - Diabetes Care, 1985 - Am Diabetes Assoc
We report our first experience with a new microprocessor device for assisting individuals with
diabetes in the adjustment of insulin therapy. The computer weighs 200 g and can receive, …