User profiles for A. F. Clark

Abbot (Abe) Clark

Regents Professor of Pharmacology & Neuroscience, U. North Texas Health Science Center
Verified email at unthsc.edu
Cited by 23024

The role of steroids in outflow resistance

AF Clark, RJ Wordinger - Experimental eye research, 2009 - Elsevier
Glucocorticoid (GC)-induced ocular hypertension and secondary iatrogenic open-angle
glaucoma are serious side effects of GC therapy. Its clinical presentation is similar in many ways …

Consensus recommendations for trabecular meshwork cell isolation, characterization and culture

…, TM Brunner, S Chansangpetch, AF Clark… - Experimental eye …, 2018 - Elsevier
Cultured trabecular meshwork (TM) cells are a valuable model system to study the cellular
mechanisms involved in the regulation of conventional outflow resistance and thus intraocular …

The many faces of the trabecular meshwork cell

WD Stamer, AF Clark - Experimental eye research, 2017 - Elsevier
With the combined purpose of facilitating useful vision over a lifetime, a number of ocular
cells have evolved specialized features not found elsewhere in the body. The trabecular …

[BOOK][B] Helium cryogenics

SW Van Sciver, KD Timmerhaus, AF Clark - 2012 - Springer
Twenty five years have elapsed since the original publication of Helium Cryogenics. During
this time, a considerable amount of research and development involving helium fluids has …

Identification of a gene that causes primary open angle glaucoma

…, JR Polansky, SLF Sunden, D Nishimura, AF Clark… - Science, 1997 - science.org
Glaucoma is a major cause of blindness and is characterized by progressive degeneration
of the optic nerve and is usually associated with elevated intraocular pressure. Analyses of …

Materials at low temperatures

RP Reed, AF Clark - 1984 - osti.gov
The aim of this volume is to establish a firm basis for the understanding of materials behavior
and property measurement to use for design and materials selection at low temperatures. …

[HTML][HTML] Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma

…, B Stevens, BA Barres, AF Clark… - The Journal of …, 2011 - Am Soc Clin Investig
Glaucoma is one of the most common neurodegenerative diseases. Despite this, the earliest
stages of this complex disease are still unclear. This study was specifically designed to …

Inherited glaucoma in DBA/2J mice: pertinent disease features for studying the neurodegeneration

…, AMY Snow, LA Wilson, RS Smith, AF Clark… - Visual …, 2005 - cambridge.org
The glaucomas are neurodegenerative diseases involving death of retinal ganglion cells
and optic nerve head excavation. A major risk factor for this neurodegeneration is a harmfully …

RETRACTED: Characterization of a transformed rat retinal ganglion cell line

…, IH Pang, D Shade, RJ Wordinger, T Yorio, AF Clark… - 2001 - Elsevier
The purpose of the present study was to establish a rat retinal ganglion cell line by transformation
of rat retinal cells. For this investigation, retinal cells were isolated from postnatal day 1 …

Glucocorticoid-induced formation of cross-linked actin networks in cultured human trabecular meshwork cells.

AF Clark, K Wilson, MD McCartney… - … & visual science, 1994 - iovs.arvojournals.org
PURPOSE: To determine the effects of glucocorticoid treatment on the microfilament
structure of cultured human trabecular meshwork cells. Topical or systemic administration of …