Recurrent histiocytic necrotizing lymphadenitis (Kikuchi's disease) in an human T lymphotropic virus type I carrier

Intern Med. 1996 Oct;35(10):821-5. doi: 10.2169/internalmedicine.35.821.

Abstract

We describe a case of recurrent histiocytic necrotizing lymphadenitis (HNL) with aseptic meningitis. The patient was a 46-year-old male and a carrier of human T lymphotropic virus type I (HTLV-I). The patient had a past medical history of at least three relapses of HNL. In addition, his sister, who was also an HTLV-I carrier, had recurrent clinical episodes consistent with those of HNL, suggesting familial HNL occurrence. This observation suggests the possibility that HTLV-I infection is relevant to the pathogenesis of HNL.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Viral / analysis
  • CD8 Antigens / immunology
  • Carrier State / virology*
  • Cell Division
  • Fatal Outcome
  • HTLV-I Infections / complications*
  • Herpesviridae Infections / complications
  • Herpesvirus 6, Human / immunology
  • Histiocytes / immunology
  • Histiocytes / pathology*
  • Human T-lymphotropic virus 1
  • Humans
  • Immunohistochemistry
  • Lewis X Antigen / immunology
  • Lymphadenitis / etiology*
  • Lymphadenitis / genetics
  • Lymphadenitis / pathology
  • Male
  • Meningitis, Aseptic / complications
  • Middle Aged
  • Necrosis
  • Pedigree
  • Recurrence

Substances

  • Antibodies, Viral
  • CD8 Antigens
  • Lewis X Antigen