Thromboembolism in a patient with transient eosinophilia

Ann Hematol. 1996 Feb;72(2):93-5. doi: 10.1007/BF00641316.

Abstract

We report here a case of thromboembolism occurring in a 29-year-old woman with transient eosinophilia. Eosinophilia for at least 11 days was followed by pulmonary embolism. Both reperfusion of pulmonary arteries and disappearance of deep vein thrombi were obtained by treatment with urokinase, tissue plasminogen activator, and heparin. Although the causes of eosinophilia were not specified, we suggested a causative correlation of elevated serum levels of eosinophil granule proteins with the development of thromboembolism.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Blood Proteins / metabolism
  • Bronchitis / blood
  • Bronchitis / complications
  • Disseminated Intravascular Coagulation / drug therapy
  • Disseminated Intravascular Coagulation / etiology
  • Drug Therapy, Combination
  • Eosinophil Granule Proteins
  • Eosinophilia / blood
  • Eosinophilia / complications*
  • Eosinophils / metabolism
  • Female
  • Heparin / therapeutic use
  • Humans
  • Pulmonary Embolism / drug therapy
  • Pulmonary Embolism / etiology*
  • Ribonucleases*
  • Thrombophlebitis / drug therapy
  • Thrombophlebitis / etiology*
  • Tissue Plasminogen Activator / therapeutic use
  • Urokinase-Type Plasminogen Activator / therapeutic use
  • Warfarin / therapeutic use

Substances

  • Blood Proteins
  • Eosinophil Granule Proteins
  • Warfarin
  • Heparin
  • Ribonucleases
  • Tissue Plasminogen Activator
  • Urokinase-Type Plasminogen Activator