Abstract
The screening method provides a simple and rapid way of estimating vaccine effectiveness. The paper discusses the validity of the screening method with particular reference to bias and precision. Methods for correcting confounding, adjusting for covariates and over-dispersion, and deriving confidence limits are discussed in a modelling framework. The methods are illustrated using data on measles and pertussis vaccines.
MeSH terms
-
Bias
-
Case-Control Studies
-
Child
-
Child, Preschool
-
Cohort Studies
-
Confidence Intervals
-
Confounding Factors, Epidemiologic
-
Humans
-
Infant
-
Logistic Models
-
Mass Screening / methods*
-
Measles / epidemiology
-
Measles / prevention & control*
-
Measles Vaccine*
-
Models, Statistical*
-
Pertussis Vaccine*
-
Population Surveillance / methods*
-
Reproducibility of Results
-
Research Design / standards*
-
Risk Factors
-
Sampling Studies
-
Whooping Cough / epidemiology
-
Whooping Cough / prevention & control*
Substances
-
Measles Vaccine
-
Pertussis Vaccine