Abstract
This investigation compares the effects of single and double doses of nitrazepam (5 and 10 mg) and zopiclone (7.5 and 15 mg) and placebo for 1 night in 40 psychiatric patients. The results indicate that zopiclone is an active hypnotic compound, comparable in its effects to those of nitrazepam, the higher dosage being best adapted to the type of patients included in the study.
Publication types
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Clinical Trial
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Comparative Study
MeSH terms
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Adolescent
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Adult
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Aged
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Azabicyclo Compounds
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Clinical Trials as Topic
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Double-Blind Method
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Emotions / drug effects
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Female
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Humans
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Hypnotics and Sedatives / therapeutic use*
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Male
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Memory / drug effects
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Mental Disorders / complications*
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Middle Aged
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Nitrazepam / adverse effects
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Nitrazepam / therapeutic use*
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Piperazines / adverse effects
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Piperazines / therapeutic use*
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Random Allocation
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Sleep Wake Disorders / drug therapy*
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Sleep Wake Disorders / etiology
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Surveys and Questionnaires
Substances
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Azabicyclo Compounds
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Hypnotics and Sedatives
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Piperazines
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zopiclone
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Nitrazepam