Congenital diaphragmatic hernia: an overview of the etiology and current management

Acta Paediatr. 2009 Apr;98(4):621-7. doi: 10.1111/j.1651-2227.2008.01212.x. Epub 2009 Jan 19.

Abstract

Aim: To review provide an overview of the etiology and current strategies in the management of congenital diaphragmatic hernia (CDH).

Methods: We did a comprehensive review of research trends, evidence based studies and epidemiologic studies.

Results: CDH is a life-threatening pathology in infants, and a major cause of death due to the pulmonary hypoplasia and pulmonary hypertension. There is much research related to elucidating the etiology of CDH and developing management strategies to improve the outcomes in these infants.

Conclusion: An early diagnosis with increased understanding of this disease is a crucial factor for a timely approach to managing the critically ill infant, and to offer the potential for improved outcomes and substantial reductions in morbidity.

Publication types

  • Review

MeSH terms

  • Hernia, Diaphragmatic / etiology
  • Hernia, Diaphragmatic / therapy*
  • Hernias, Diaphragmatic, Congenital*
  • Humans
  • Infant, Newborn