Malignant glomus tumor of the hand

Appl Immunohistochem Mol Morphol. 2009 May;17(3):264-9. doi: 10.1097/PAI.0b013e31818a9d5d.

Abstract

Malignant glomus tumors, or glomangiosarcomas, are rare soft tissue tumors and usually represent a locally infiltrative malignancy. They have been reported in many different anatomic locations with the lower extremity and abdominal viscera being the most common. Their location in the hand is extremely rare. Glomangiosarcomas tend to pursue a benign course with local aggressiveness. However, metastasis can occur and is associated with a poor prognosis. Different classification systems have been proposed based on histologic criteria. We present an unusually large, aggressive glomangiosarcoma at the tip of the long finger in a 33-year-old pregnant woman.

Publication types

  • Case Reports

MeSH terms

  • Actins / analysis
  • Adult
  • Female
  • Fingers / pathology*
  • Fingers / surgery
  • Glomus Tumor / pathology*
  • Glomus Tumor / surgery
  • Humans
  • Pregnancy
  • Pregnancy Complications, Neoplastic / pathology*
  • Pregnancy Complications, Neoplastic / surgery
  • Proto-Oncogene Proteins c-bcl-2 / analysis
  • Sarcoma / pathology*
  • Sarcoma / surgery
  • Soft Tissue Neoplasms / pathology*
  • Soft Tissue Neoplasms / surgery

Substances

  • Actins
  • Proto-Oncogene Proteins c-bcl-2