The majority of ectopic pregnancies are located within the fallopian tube. Nevertheless, pregnancies have been reported to implant in the cervix, ovary, interstitial tubal segment, and at various intra-abdominal sites. The diagnosis and treatment of these unusual implantation sites presents both diagnostic and therapeutic dilemmas. The majority of data regarding these unusual ectopic pregnancies come largely from case reports and anecdotal information. In the past, treatment of these ectopic pregnancies used various combinations of surgery and/or systemic and local chemotherapy. In this article, we attempt to summarize the current data regarding diagnosis and optimal treatment of these unusual ectopic pregnancies.