Acute generalized exanthematous pustulosis following a spider bite: report of 3 cases

Batya B Davidovici; Dyachenko Pavel; Emanuela Cagnano; Dganit Rozenman; Sima Halevy; EuroSCAR; RegiSCAR study group

doi:10.1016/j.jaad.2006.05.010

Acute generalized exanthematous pustulosis following a spider bite: report of 3 cases

J Am Acad Dermatol. 2006 Sep;55(3):525-9. doi: 10.1016/j.jaad.2006.05.010.

Authors

Batya B Davidovici¹, Dyachenko Pavel, Emanuela Cagnano, Dganit Rozenman, Sima Halevy; EuroSCAR; RegiSCAR study group

Affiliation

¹ Department of Dermatology, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

PMID: 16908368
DOI: 10.1016/j.jaad.2006.05.010

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction caused mostly by drugs. Three of 22 AGEP cases (13.6%), recruited by us as part of two prospective multinational studies, occurred 24 to 48 hours after a spider bite. We suggest that a spider bite is a possible trigger for AGEP.

Publication types

Case Reports

MeSH terms

Acute Disease
Adult
Exanthema / etiology*
Exanthema / pathology
Female
Humans
Male
Skin / pathology
Skin Diseases, Vesiculobullous / etiology*
Skin Diseases, Vesiculobullous / pathology
Spider Bites / complications*
Time Factors