Heparin and insulin in the treatment of hypertriglyceridemia-induced severe acute pancreatitis

Hakan Alagözlü; Mehmet Cindoruk; Tarkan Karakan; Selahattin Unal

doi:10.1007/s10620-005-9006-z

Heparin and insulin in the treatment of hypertriglyceridemia-induced severe acute pancreatitis

Dig Dis Sci. 2006 May;51(5):931-3. doi: 10.1007/s10620-005-9006-z. Epub 2006 May 3.

Authors

Hakan Alagözlü¹, Mehmet Cindoruk, Tarkan Karakan, Selahattin Unal

Affiliation

¹ Department of Internal Medicine, Division of Gastroenterology, Medical Faculty of Gazi University, Ankara, Turkey. hakanalagoz@gazi.edu.tr

PMID: 16670939
DOI: 10.1007/s10620-005-9006-z

Abstract

Heparin and insulin stimulate lipoprotein lipase activity. Therefore, they reduce serum triglyceride levels. However, heparin and insulin's efficacy in treatment of hypertriglyceridemia-induced acute pancreatitis is not well established. We report a patient in whom heparin and insulin were used successfully.

Publication types

Case Reports

MeSH terms

Adult
Anticoagulants / pharmacology
Anticoagulants / therapeutic use*
Drug Therapy, Combination
Heparin / pharmacology
Heparin / therapeutic use*
Humans
Hypertriglyceridemia / complications*
Hypoglycemic Agents / pharmacology
Hypoglycemic Agents / therapeutic use*
Insulin / pharmacology
Insulin / therapeutic use*
Lipoprotein Lipase / drug effects
Male
Pancreatitis / blood
Pancreatitis / drug therapy*
Pancreatitis / etiology

Substances

Anticoagulants
Hypoglycemic Agents
Insulin
Heparin
Lipoprotein Lipase