Monoclonal antibody successes in the clinic

Nat Biotechnol. 2005 Sep;23(9):1073-8. doi: 10.1038/nbt0905-1073.

Abstract

Most monoclonal antibodies in clinical trials are owned by small biotech companies. But with blockbuster-sized revenues and approval rates higher than those for small-molecule drugs, that all may be set to change.

MeSH terms

  • Animals
  • Antibodies, Monoclonal / chemistry
  • Antibodies, Monoclonal / therapeutic use*
  • Biotechnology / methods
  • Biotechnology / trends
  • Chemistry, Pharmaceutical / trends
  • Clinical Trials as Topic
  • Drug Approval
  • Drug Industry / trends
  • Humans
  • Hybridomas / metabolism
  • Immunotherapy / methods*
  • Neoplasms / therapy
  • United States
  • United States Food and Drug Administration

Substances

  • Antibodies, Monoclonal