Acquired factor VIII inhibitor presenting as a tongue hematoma

Catherine M Wendell; Marc A Bellazzini; David S Howes

doi:10.1016/j.jemermed.2003.11.021

Acquired factor VIII inhibitor presenting as a tongue hematoma

J Emerg Med. 2004 May;26(4):411-4. doi: 10.1016/j.jemermed.2003.11.021.

Authors

Catherine M Wendell¹, Marc A Bellazzini, David S Howes

Affiliation

¹ Section of Emergency Medicine, University of Chicago, Chicago, Illinois, USA.

PMID: 15093846
DOI: 10.1016/j.jemermed.2003.11.021

Abstract

Acquired hemophilia is a rare disorder that has potentially disastrous consequences if not recognized and treated in the setting of acute hemorrhage. We report a case of undiagnosed acquired hemophilia due to factor VIII inhibitor in which a tongue hematoma was the chief manifestation. Diagnosis, acute management, and long-term therapeutic options are reviewed.

Publication types

Case Reports

MeSH terms

Aged
Blood Coagulation Factors / therapeutic use
Factor VIII / antagonists & inhibitors*
Female
Hematoma / etiology*
Hemophilia A / complications*
Hemophilia A / drug therapy
Humans
Partial Thromboplastin Time
Tongue Diseases / etiology*

Substances

Blood Coagulation Factors
prothrombin complex concentrates
Factor VIII