MDMA (Ecstasy) precipitation of panic disorder

Biol Psychiatry. 1992 Jul 1;32(1):91-5. doi: 10.1016/0006-3223(92)90145-p.

Abstract

The authors describe three patients whose panic disorder began during recreational use of MDMA (Ecstasy) and was subsequently complicated by agoraphobic avoidance that continued autonomously after cessation of the drug. Their panic disorder responded well to serotoninergic antidepressant drugs. Theoretical and practical implications are discussed.

Publication types

  • Case Reports

MeSH terms

  • 3,4-Methylenedioxyamphetamine / adverse effects
  • 3,4-Methylenedioxyamphetamine / analogs & derivatives*
  • Adult
  • Agoraphobia / chemically induced
  • Agoraphobia / drug therapy
  • Agoraphobia / psychology
  • Alcohol Drinking / adverse effects
  • Amitriptyline / therapeutic use
  • Arousal / drug effects
  • Fluvoxamine / therapeutic use
  • Humans
  • Male
  • N-Methyl-3,4-methylenedioxyamphetamine
  • Panic Disorder / chemically induced*
  • Panic Disorder / drug therapy
  • Panic Disorder / psychology
  • Recurrence
  • Substance Withdrawal Syndrome / drug therapy
  • Substance Withdrawal Syndrome / psychology*
  • Tranylcypromine / therapeutic use

Substances

  • Amitriptyline
  • Tranylcypromine
  • 3,4-Methylenedioxyamphetamine
  • N-Methyl-3,4-methylenedioxyamphetamine
  • Fluvoxamine