Urine specific gravity measurement: reagent strip versus refractometer

Clin Lab Sci. 1994 Sep-Oct;7(5):308-10.

Abstract

Objective: To compare the results of urinalysis screenings for specific gravity (SG) using the reagent strip and the refractometer.

Setting: United Hospital, Grand Forks, North Dakota.

Practice description: United Hospital is a 384-bed teaching hospital. PRODUCT COMPARISON: The Ames Multistix 10 SG reagent strip (Miles, Inc., Elkhart, IN 46515) was compared with the TS Meter (Leica, Inc., Deerfield, IL 60015).

Main outcome measurement: The degree of correlation between the results produced by each method.

Results: The percentage of difference between the means of the direct strip readings and the refractometer readings was 9.68%. The percentage of difference between the means of the adjusted strip readings and the refractometer readings was 22.58%, which was significantly different. When the direct strip readings and the refractometer readings were plotted together on a graph, the points were widely scattered; this fact, and a correlation coefficient of 0.725, suggest that random error occurred in both methods. Analysis of the slope and intercept of the correlation indicated systematic error.

Conclusion: The reagent strip method of measuring SG is accurate only in a narrow range of "average" values, and should not be used as the basis for medical diagnoses.

Publication types

  • Comparative Study

MeSH terms

  • Humans
  • Reagent Strips*
  • Refractometry*
  • Specific Gravity
  • Urinalysis / methods*

Substances

  • Reagent Strips