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Topical anesthetics

Physiology, formulations, and novel delivery systems

  • Technology in Practice
  • Published:
American Journal of Drug Delivery

Abstract

Topical anesthetics have become valuable tools in the field of dermatology, especially in pediatric patients, who have particular need for such anesthesia. The ideal topical anesthetic should provide effective, painless cutaneous analgesia with quick onset, sufficient duration and minimal adverse effects. This article reviews the basic science concepts relevant to the safe and judicious use of topical anesthetic agents in children, examines the specific characteristics and practical uses of these agents, and discusses the various unique delivery systems currently available.

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Notes

  1. The use of trade names is for product identification purposes only and does not imply endorsement.

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The authors have provided no information on sources of funding or on conflicts of interest directly relevant to the content of this manuscript.

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Authors and Affiliations

  1. Pediatric and Adolescent Dermatology, Children’s Hospital and Health Center, 8010 Frost Street, Suite 602, San Diego, CA, 92123, USA

    Tsippora Shainhouse &  Bari B. Cunningham

  2. Pediatrics and Medicine (Dermatology), Children’s Hospital and Health Center and University of California, San Diego, San Diego, California, USA

    Bari B. Cunningham

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  1. Tsippora Shainhouse
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Correspondence to Bari B. Cunningham.

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Shainhouse, T., Cunningham, B.B. Topical anesthetics. Am J Drug Deliv 2, 89–99 (2004). https://doi.org/10.2165/00137696-200402020-00002

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