APSA PapersLong-term surgical outcomes in congenital diaphragmatic hernia: observations from a single institution
Section snippets
Methods
Permission for this study was obtained from the Committee on Human Research of the University of California, San Francisco (UCSF), H11258-30536-01.
Cohort characteristics
General cohort characteristics are presented in Table 1. There was 1 postdischarge death occurring in a 21-month-old boy owing to delayed transfer to UCSF for management of volvulus. For the purposes of statistical analysis, perinatal predictors of adverse surgical outcomes were given the following binary classifications: patch vs primary repair, liver herniation vs no herniation, age at extubation greater or less than 16 days (cohort median), neonatal discharge with or without oxygen
Discussion
Surgical complications are common among CDH survivors, but data are limited regarding long-term incidence patterns and associated risk factors [4], [5], [7], [8], [12], [13], [14], [15], [16]. As with the adverse medical outcomes of neurodevelopmental delay, hearing loss, pulmonary insufficiency, and growth and nutritional failure, adverse surgical outcomes seem to be most frequent in those patients with a large CDH defect requiring patch repair. In keeping with existing reports, in our cohort
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Presented at the 40th Annual Meeting of the American Pediatric Surgical Association, Fajardo, Puerto Rico, May 28-June 1, 2009.