Phytophotodermatitis

doi:10.1016/S1046-199X(99)90006-4

American Journal of Contact Dermatitis

Volume 10, Issue 2, June 1999, Pages 89-93

https://doi.org/10.1016/S1046-199X(99)90006-4 Get rights and content

Abstract

This article is a concise review of phytophotodermatitis, including the mechanism involved, clinical features, and treatment options. The common culprit plant families of Umbelliferae, Rutaceae, and Moraceae are discussed along with the newly recognized St. John's Wort.

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There are more references available in the full text version of this article.

Cited by (68)

The chemical composition of the aerial parts essential oil of Ammi crinitum Guss. (Apiaceae) endemic of Sicily (Italy)
2024, Natural Product Research
Ammi L. is a small genus of economically important plants belonging to Apiaceae family that includes only six taxa. In the present study the chemical composition of the essential oil from aerial parts of Ammi crinitum Guss., a very rare plant, endemic of Sicily, was analyzed by GC–MS. No previously paper has been published on this species. The results showed the presence of large quantity of monoterpene hydrocarbons with sabinene (63.9%), as the most abundant component. Other metabolites present in good quantity were γ-terpinene (8.0%), and 4-terpineol (3.7%). Based on the composition of the essential oil of all the other Ammi taxa, several considerations have been carried out.
Erythematous papules of the back
2022, Revue de Medecine Interne
Aatrilal (Ammi majus L.), an important drug of Unani system of medicine: A review
2021, Journal of Ethnopharmacology
Ammi majus L. (Aatrilal) a member of the family Apiaceae, is native to Egypt and widely distributed in Europe, the Mediterranean, and West Asia. It has been used for the treatment of various dermatological disorders particularly vitiligo in the Unani system of Medicine for ages. In traditional medicine, fruits are used as an emmenagogue as well as a diuretic, blood purifier and to treat leprosy, urinary and digestive disorders.
This paper aims to highlight the medicinal properties of Aatrilal in view of its temperament and phytoconstituents; to signify its potential in the treatment of vitiligo and other ailments as mentioned in Unani system of medicine and also to explore its phytochemistry, pharmacological and clinical studies.
Aatrilal was explored in classical Unani literature for its temperament (mizaj), medicinal properties and therapeutic uses. Published works available on PubMed, Science Direct, and Google Scholar were referred to collect all the available information regarding its phytochemicals and pharmacological studies. All relevant articles up to 2020 were referred including 15 classical Unani books, 15 English books, 72 research, and 3 review papers. The plant's scientific names were validated using ‘The Plant List’ (www.theplantlist.org). Standard Unani Medical Terminology published by Central Council for Research in Unani Medicine in collaboration with the World Health Organization was used to describe the appropriate Unani terminologies. Glossary of Indian Medicinal Plants and different indexed journals were consulted for botanical and English names.
Aatrilal has been used in traditional medicine for ages. Due to controversies in its identity, it was adulterated and substituted with many drugs. The real identity of Aatrilal is now established as the fruit of A. majus L. Despite having numerous pharmacological activities, it is considered the first-line drug for the treatment of vitiligo. It is a rich source of furanocoumarins (xanthotoxin, also known as 8-methoxypsoralen, bergapten, imperatorin, isopimpinellin) with other compounds viz. flavonoids, terpenoids, proteins, essential oil constituents, etc. It has been reported for anti-inflammatory, analgesic, antibacterial, antiviral, cytotoxic, and many other activities. Clinical trials have shown the therapeutic potential in vitiligo and other skin disorders.
Based on the available literature, it can be concluded that Aatrilal is a drug that has been effectively used in Unani system of medicine for centuries to treat the cases of vitiligo and other dermatological disorders. It has been studied extensively for its phytopharmacological properties. Raw extracts of A. majus form the crux of the main research. Many potentially bioactive compounds are included in the essential oil, but to our knowledge, no detailed studies of its biological activity are yet available. Therefore, our suggestion is to focus future research on essential oil and its ingredients.
Phytophotodermatosis with parsnip: A case report
2020, Journal de Pediatrie et de Puericulture
Les phytophotodermatoses sont des éruptions cutanées résultant du contact avec des composés photosensibilisants présents dans diverses plantes et d’une exposition solaire. Nous rapportons le cas d’une phytophotodermatose survenue chez un enfant de 6 mois, 12 h après l’ingestion d’une purée de panais cuite prise en extérieure au printemps. Le traitement est essentiellement symptomatique. Des complications à type d’hyperpigmentation cutanée résiduelles sont fréquentes.
Phytophotodermatoses are rashes resulting from contact with photosensitizing compounds in various plants and sun exposure. We report the case of a phytophotodermatosis occurred in a child of 6 months, 12 hours after the ingestion of a purée of cooked parsnip taken outside in the spring. The treatment is essentially symptomatic. Complications such as residual skin hyperpigmentation are common.
Plant Associated Irritant & Allergic Contact Dermatitis (Phytodermatitis)
2020, Dermatologic Clinics
Citation Excerpt :
The cutaneous manifestations may occur on perioral skin from consumption or on the hands or arms from inadvertent spilling. Interestingly, pruritus is often not as pronounced as with ACD, which can be helpful in differentiating phytophotodermatitis from other forms of phytodermatitis, such as poison ivy.5 Other forms of phytophotodermatitis include strimmer dermatitis or weed-eater dermatitis, which results from exposure to psoralens being flung on exposed skin during lawn trimming or weeding.6
Wild parsnip (Pastinaca sativa)-induced photosensitization
2019, Toxicon
Wild parsnip (Pastinaca sativa) has been associated with livestock and human photosensitization. An investigation of a natural occurrence of photosensitization of grazing horses identified wild parsnip as a possible cause. HPLC-MS and MS/MS analysis of this plant identified five furanocoumarins i.e., xanthotoxin, bergapten, isopimpinellin, imperatorin and a putative methoxyimperatorin. Goats fed this wild parsnip were largely unaffected. Xanthotoxin was not detected in the serum of parsnip-fed goats or in the serum of goats dosed orally or intravenous with purified xanthotoxin. Cutaneous application produced severe photodermatitis in goats and a horse consistent with topical exposure as the likely route to produce wild parsnip-induced photosensitivity. Wild parsnip-induced superficial necrotizing dermatitis was consistent with photodermatitis with no evidence of other allergic or inflammatory components.

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Plant talkPhytophotodermatitis

Abstract

J Pharm Sci

Phytochem

Food Chem Toxic

Phyto-photo-dermatitis

Br J Dermatol

Plants and the Skin

Recent advances in psoralen phototoxicity mechanism

Photochem Photobiol

Plants and the Skin

Phytophotodermatitis from mokihana fruits in Hawaiian lei

Contact Dermatitis

Strimmer rash

Contact Dermatitis

Plants and the Skin

Plant talk
Phytophotodermatitis