Original researchOral versus intramuscular cobalamin treatment in megaloblastic anemia: A single-center, prospective, randomized, open-label study
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Evaluation of the professional practices of specialized obesity centers on the strategy of vitamin B12 follow-up and supplementation after obesity surgery
2022, Nutrition Clinique et MetabolismeCitation Excerpt :We observed a tendency to favor the use of the oral route, but there is no clear predominance either in the attack phase or in the maintenance phase. It is interesting to note that the doses used by the interviewed practitioners are generally much lower than the ones used in the studies that have compared oral and intramuscular treatment methods [11–14]. In the absence of clear recommendations, most practitioners rely on their department habits.
Significant increase of serum B12 levels with high-dose oral vitamin B12 supplementation with or without intrinsic factor after Roux-en-Y gastric bypass: A randomized controlled trial
2022, Obesity MedicineCitation Excerpt :This trial confirms that passive diffusion due to a high oral vitB12 dosage compensates for the food-bound vitB12 malabsorption in RYGB in patients with start values within the normal ranges. The equal efficacy of high-dose oral vitB12 supplements as opposed to intramuscular injections had already been demonstrated in multiple RCT's for vitB12 deficiency in the general population (Bolaman et al., 2003; Castelli et al., 2011). Results of this trial support extrapolation of these principles to the RYGB population.
Routes of administration of vitamin B<inf>12</inf>
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