Elsevier

The Lancet

Volume 335, Issue 8684, 3 February 1990, Pages 241-246
The Lancet

MEDICAL SCIENCE
Edinburgh trial of screening for breast cancer: mortality at seven years

https://doi.org/10.1016/0140-6736(90)90066-EGet rights and content

Abstract

Between 1979 and 1981, 45130 women in Edinburgh aged 45-64 were entered into a randomised trial of breast cancer screening by mammography and clinical examination. The initial attendance rate was 61% but this varied according to age and socioeconomic status and decreased over succeeding years. The cancer detection rate was 6·2 per 1000 women attending at the first visit; the rate fell to around 3 per 1000 in the years when mammography was routinely repeated and to around 1 per 1000 at the intervening visits with clinical examination alone as the screening method. After 7 years of follow-up the mortality reduction achieved was 17% (relative risk=0·83, 95% Cl 0·58-1·18), which was not statistically significant, even when corrected for socioeconomic status. In women aged 50 years and over a mortality reduction of 20% was achieved.

References (26)

  • Mm Roberts et al.

    The Edinburgh Health Education Campaign on breast cancer and self-examination: was it worthwhile?

    J Epidemiol Community Health

    (1986)
  • U. Maclean et al.

    Women who decline breast screening

    J Epidemiol Community Health

    (1984)
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